Understanding Rifampin

I think I just found the reasoning behind why Dr. Singleton writes in is book The Lyme Disease Solution to take Rifampin 3 hours away from other medicine. I found this by re-reading Dr. Burrascano's 2008 Guidelines in which he states in regards to Rifampin:

"Finally, because this drug (Rifampin) is an inducer of cytochromes, co-administration with other medications may result in lower and more brief blood levels of the coadministred drug".

Basically, it will get rid of the Doxy in my blood if I take them together so definitely a good idea to separate them as Dr. Terese Yang advises as well.