What we know about Lyme is that inhibits the pathway in which the body metabolizes tryptophan from food. It takes what would naturally turn into tryptophan and turns it into a neurotoxin. Tryptophan gives us calm, upbeat, happy feelings and makes the neurotransmitter Serotonin.
Okay. So I tested positive for Lyme. But not Bartonella. However, when I began treating the Bartonella with Rifampin, two "cat scratch" like marks with non-blanching centers appeared on my forearm on the exact opposite side of my forearm than the bulls-eye lyme rash that appeared 1 days into taking Doxycycline. My LLND suspected I had Bartonella, even though I didn't blood test positive for it, because of my severe anxiety issues that is usually a clue that you have Bartonella.
But what causes the anxiety? Here is my thought. Lyme causes you to be depressed feeling via the change in the Tryptophan/Serotonin pathway. Does Bartonella cause anxiety/panic via the Phenylalinine (Tyrosine)/Norephinephrine pathway? Phenylalanine and Tyrosine are involved in Neurotransmitters as well producing alert, calm feelings.
On my Organic Acid Test, it indiciates very, very high levels of the p-Hydroxyphelacetate which is not considered "normal". I found some information on this organic acid on a website that explains the organic acid test. This is what it says:
For individuals with normal, healthy intestinal function, these compounds (p-Hydroxybenzoate, p-Hydroxypheylacetate, Tricarballylate) should not appear at more than background concentrations in urine due to the efficient metabolic conservation or recycling of phenyl group compounds of which they are composed. They are produced by microbial action on tyrosine and phenylalanine and are markers of backterial growth in the gut.
So there is a bacteria in my gut that is preying on my phenylalanine and tyrosine. Could it be Bartonella? Has anybody else with Bartonella had an Organic Acid Test and had similar results? If they have, and they have high levels of this particular organic acid could it be an indirect way to test for the Bartonella organism that often evades basic blood testing. I am just curious. Kind of like how CD-57 is an indirect way to test for the presence of Chronic Lyme, could OAT (Organic Acid Testing) be an indirect way to test for the presence of Bartonella? Maybe. Just a thought.
By the way, Phenylacetate was very high as well, as high as p-Hydroxyphenylacetate. Just a FYI.
I was wondering if you ever figured this out?
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